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Place of work

Campus Innenstadt

Working hours

Full time

Establishment

Abteilung für Infektions- und Tropenmedizin

area

Forschung

Date of entry

01.01.2021

Application deadline

21.09.2020

Reference Number

2020-K-0324

The Hospital of the University of Munich, Germany, is one of the largest and most competitive university hospitals in Germany and Europe. 48 specialized hospitals, departments and institutions harbouring excellent research and education provide patient care at the highest medical level with approximately 10.000 employees.

Scope of duties

  • The planned PhD project aims at identifying host genetic polymorphisms as well as transcriptomic signatures associated with patient differences in the tuberculosis treatment response and clinical outcomes using genome wide association study (GWAS) and next generation sequencing approaches. This personalized medicine project is embedded within the BMBF funded TB sequel study (https://www.tbsequel.org/), which studies the sequelae of tuberculosis in 1600 patients from 4 sub-Saharan African countries.
  • The planned PhD project will be conducted as a collaboration of the Division of Infectious Diseases and Tropical Medicine (DIDTM), the Institute of Translational Genomics at the Helmholtz Centre Munich (https://www.helmholtz-muenchen.de/en/itg/index.html) and the TB sequel study consortium partners.
  • The PhD candidate will be embedded in the “Infection & Immunity” research group (https://tinyurl.com/Geldmacher-Held) at the DIDTM and associated DZIF international clinical trials unit, which specializes in large human cohort research in the field of vaccines, diagnostics and therapeutics in infectious diseases.

Our requirements

  • Highly qualified and motivated applicants should hold the equivalent of a masters' degree in bioinformatics, computational biology, biostatistics or related fields
  • Programming skills in at least one programming language (such as R, Python, or Perl) for biological data analysis is of advantage
  • Experience in the analysis of complex datasets such as GWAS or NGS as well as the ability to handle large datasets (big data) is desired
  • Familiarity with common bioinformatics databases and tools and knowledge of fundamental biological and statistical concepts would be a plus
  • Proficiency in English speaking and writing, as well as good team and communication skills are required

Our offer

  • We offer a versatile international and interdisciplinary environment in a young and motivated translational research group and training in cutting edge bioinformatic techniques
  • The Ludwig-Maximilians-Universität as well as the Helmholtz Centre Munich offer various formal PhD curricula. Salary is based on TV-L
  • Individuals of all nationalities, genders, ages, and those with disabilities are encouraged to apply
  • We give priority to applicants with a disability and essentially equal qualifications
  • Presentation costs cannot be refunded

Contact for questions

PD Dr. Christof Geldmacher and PD Dr. med. Andrea Rachow

 

E-Mail

Application address

LMU Clinic

Division of Infectious Diseases and Tropical Medicine

 

Leopoldstrasse 5

80802

Munich


Disabled persons will be preferentially considered in case of equal qualification. Presentation costs cannot be refunded. 

Links: https://www.lmu-klinikum.de/stellenanzeigen/neue-stellenanzeige/1fb292e88b742436

 

 

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