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NEB-research has an opening for a highly motivated Postdoctoral Associate in experimental and Computational Biology. The major topic of the team is to bridge the large enzyme discovery and optimization efforts with the latest massive parallel sequencing technologies. With the central aim to develop innovative large scale applications, the team research involves the elaboration of both experimental methodologies and data analysis strategies inherent to such applications. The outcomes of these efforts are twofold: first, the perspective of a major leap into existing or novel technologies and second, the unique abilities to address biological questions

Your primary focus will be on developing screening technologies to uniquely identify and sequence organisms harboring non-canonical nucleotides in microbiomes. Indeed, a number of microorganisms notably phages have been using non-canonical nucleotides in their genomes to evade the bacteria immune system. The discovery of such organisms has been seldom and so far no systematic investigation of the number of organisms with modified DNA nor the nature of such modifications has been conducted on a microbiome.  This study will provide information on the prevalence and pathways involved. You will be working both on the experimental and analysis front of the project.

Skills & Experience
• Ph.D. or equivalent in Computational biology, molecular biology, biochemistry or related field.
• Expertise in large scale data analysis and programming. Expertise in microbiome studies is a plus.
• Expertise in working with nucleotides and nucleic acid.
• Collaborative minded.
• Good interdisciplinary communication skills.

If interested, please contact Dr. Laurence Ettwiller : Diese E-Mail-Adresse ist vor Spambots geschützt! Zur Anzeige muss JavaScript eingeschaltet sein!